The role of denosumab in the prevention of hypercalcaemia of malignancy in cancer patients with metastatic bone disease.
Identifieur interne : 002713 ( Main/Exploration ); précédent : 002712; suivant : 002714The role of denosumab in the prevention of hypercalcaemia of malignancy in cancer patients with metastatic bone disease.
Auteurs : Ingo J. Diel [Allemagne] ; Jean-Jacques Body [Belgique] ; Alison T. Stopeck [États-Unis] ; Saroj Vadhan-Raj [États-Unis] ; Andrew Spencer [Australie] ; Günther Steger [Autriche] ; Roger Von Moos [Suisse] ; François Goldwasser [France] ; Amy Feng [États-Unis] ; Ada Braun [États-Unis]Source :
- European journal of cancer (Oxford, England : 1990) [ 1879-0852 ] ; 2015.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Anticorps monoclonaux humanisés (usage thérapeutique), Diphosphonates (usage thérapeutique), Dénosumab, Femelle, Humains, Hypercalcémie (), Imidazoles (usage thérapeutique), Modèles de hasards proportionnels, Myélome multiple (anatomopathologie), Myélome multiple (sang), Mâle, Méthode en double aveugle, Tumeurs (anatomopathologie), Tumeurs (sang), Tumeurs du sein (anatomopathologie), Tumeurs du sein (sang), Tumeurs osseuses (sang), Tumeurs osseuses (secondaire).
- MESH :
- anatomopathologie : Myélome multiple, Tumeurs, Tumeurs du sein.
- sang : Myélome multiple, Tumeurs, Tumeurs du sein, Tumeurs osseuses.
- secondaire : Tumeurs osseuses.
- usage thérapeutique : Anticorps monoclonaux humanisés, Diphosphonates, Imidazoles.
- Adulte d'âge moyen, Dénosumab, Femelle, Humains, Hypercalcémie, Modèles de hasards proportionnels, Mâle, Méthode en double aveugle.
English descriptors
- KwdEn :
- Antibodies, Monoclonal, Humanized (therapeutic use), Bone Neoplasms (blood), Bone Neoplasms (secondary), Breast Neoplasms (blood), Breast Neoplasms (pathology), Denosumab, Diphosphonates (therapeutic use), Double-Blind Method, Female, Humans, Hypercalcemia (prevention & control), Imidazoles (therapeutic use), Male, Middle Aged, Multiple Myeloma (blood), Multiple Myeloma (pathology), Neoplasms (blood), Neoplasms (pathology), Proportional Hazards Models.
- MESH :
- chemical , therapeutic use : Antibodies, Monoclonal, Humanized, Diphosphonates, Imidazoles.
- blood : Bone Neoplasms, Breast Neoplasms, Multiple Myeloma, Neoplasms.
- pathology : Breast Neoplasms, Multiple Myeloma, Neoplasms.
- prevention & control : Hypercalcemia.
- secondary : Bone Neoplasms.
- chemical : Denosumab, Double-Blind Method, Female, Humans, Male, Middle Aged, Proportional Hazards Models.
Abstract
We compared the activity of denosumab with zoledronic acid for delaying or preventing hypercalcaemia of malignancy (HCM) in patients with advanced cancer and bone metastases or with multiple myeloma.
DOI: 10.1016/j.ejca.2015.04.017
PubMed: 25976743
Affiliations:
- Allemagne, Australie, Autriche, Belgique, France, Suisse, États-Unis
- Bade-Wurtemberg, Californie, District de Karlsruhe, Région de Bruxelles-Capitale, Texas, Vienne (Autriche), État de New York, Île-de-France
- Bruxelles, Mannheim, Paris, Vienne (Autriche)
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Le document en format XML
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Diel</name><affiliation wicri:level="3"><nlm:affiliation>Center for Gynecological Oncology, Mannheim, Germany. 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wicri:level="1"><nlm:affiliation>The Alfred Hospital, Prahran, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>The Alfred Hospital, Prahran, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Steger, Gunther" sort="Steger, Gunther" uniqKey="Steger G" first="Günther" last="Steger">Günther Steger</name><affiliation wicri:level="3"><nlm:affiliation>Medical University of Vienna, Vienna, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Medical University of Vienna, Vienna</wicri:regionArea><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Von Moos, Roger" sort="Von Moos, Roger" uniqKey="Von Moos R" first="Roger" last="Von Moos">Roger Von Moos</name><affiliation wicri:level="1"><nlm:affiliation>Kantonsspital 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(blood)</term><term>Bone Neoplasms (secondary)</term><term>Breast Neoplasms (blood)</term><term>Breast Neoplasms (pathology)</term><term>Denosumab</term><term>Diphosphonates (therapeutic use)</term><term>Double-Blind Method</term><term>Female</term><term>Humans</term><term>Hypercalcemia (prevention & control)</term><term>Imidazoles (therapeutic use)</term><term>Male</term><term>Middle Aged</term><term>Multiple Myeloma (blood)</term><term>Multiple Myeloma (pathology)</term><term>Neoplasms (blood)</term><term>Neoplasms (pathology)</term><term>Proportional Hazards Models</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Anticorps monoclonaux humanisés (usage thérapeutique)</term><term>Diphosphonates (usage thérapeutique)</term><term>Dénosumab</term><term>Femelle</term><term>Humains</term><term>Hypercalcémie ()</term><term>Imidazoles (usage thérapeutique)</term><term>Modèles de hasards proportionnels</term><term>Myélome multiple 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moyen</term><term>Dénosumab</term><term>Femelle</term><term>Humains</term><term>Hypercalcémie</term><term>Modèles de hasards proportionnels</term><term>Mâle</term><term>Méthode en double aveugle</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We compared the activity of denosumab with zoledronic acid for delaying or preventing hypercalcaemia of malignancy (HCM) in patients with advanced cancer and bone metastases or with multiple myeloma.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Autriche</li><li>Belgique</li><li>France</li><li>Suisse</li><li>États-Unis</li></country><region><li>Bade-Wurtemberg</li><li>Californie</li><li>District de Karlsruhe</li><li>Région de Bruxelles-Capitale</li><li>Texas</li><li>Vienne (Autriche)</li><li>État de New York</li><li>Île-de-France</li></region><settlement><li>Bruxelles</li><li>Mannheim</li><li>Paris</li><li>Vienne 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